The Dynamic Duo for Colds & Flu References and Legals
- Health Canada: Natural health product monograph for Elder – Sambucus [Online]. Available from: https://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq?atid=elder.sureau&lang=eng. Accessed 1 March, 2025.
- Sanlier N, Ejder ZB, Irmak E. Are the effects of bioactive components on human health a myth?: Black elderberry (Sambucus nigra L.) from exotic fruits. Curr Nutr Rep. 2024;13:815–827. doi: 10.1007/s13668-024-00572-6.
- Marțiș GS, Mureșan V, Marc RM, et al. The physicochemical and antioxidant properties of Sambucus nigra L. and Sambucus nigra Haschberg during growth phases: From buds to ripening. 2021;10:1093. doi: 10.3390/antiox10071093.
- Wieland LS, Piechotta V, et al. Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review. BMC Complement Med Ther. 2021;21:112. https://doi.org/10.1186/s12906-021-03283-5
- European Medicines Agency: Ivy leaf – Hedera helix L., folium [Online]. Accessed 1 March, 2025.
- Seifert G, Upstone L, Watling CP, Vogelberg C. Ivy leaf dry extract EA 575 for the treatment of acute and chronic cough in pediatric patients: review and expert survey. Curr Med Res Opin. 2023;39:1407–1417.
- Kostev K, Völp A, Ludwig F, et al. Association between ivy leaves dry extract EA 575 prescriptions and antibiotic use, sick leave duration, and repeated infections in adult patients. Postgrad Med. 2022;134:333–340.
- de Faria Coelho-Ravagnani C, Campos Corgosinho F, et al. Dietary recommendations during the COVID-19 pandemic. Nutr Rev. 2021;79:382–393. doi: 10.1093/nutrit/nuaa067.
- Bramley TJ, Lerner D, Sames M. Productivity losses related to the common cold. J Occup Environ Med. 2002;44:822–829. doi: 10.1097/00043764-200209000-00004.
S0] Vital® COLD & FLU PLUS effervescent tablets. Each effervescent tablet contains 1300 mg Sambucus nigra L. (Elderberry fruit) [as 65 mg of a 20:1 extract]; 1000 mg Vitamin C; 12 mg Zinc; 11 mg Vitamin B2; 300 µg RE Vitamin A and 10 µg Vitamin D3. Combination product – Western herbal medicine / Health supplement. This unregistered medicine has not been evaluated by the SAHPRA for its quality, safety or intended use. Vital Health Foods (Pty) Ltd, Reg. no.: 51/03081/07. Vineyard Office Estate, 99 Jip De Jager Drive, De Bron, Cape Town, 7530, South Africa. Tel no.: 0800 22 3311. Please refer to the detailed professional information (PI) for full prescribing information.
[S0] Vital® COUGH PLUS syrup. Each 5 ml syrup contains 1440 mg Sambucus nigra L. (Elderberry fruit) [as 45 mg of a 32:1 extract] and 150 mg Hedera helix L. (Ivy leaf)[as 30 mg of a 5-7,5:1 extract]. Western herbal medicine. This unregistered medicine has not been evaluated by the SAHPRA for its quality, safety or intended use. Vital Health Foods (Pty) Ltd, Reg. no.: 51/03081/07. Vineyard Office Estate, 99 Jip De Jager Drive, De Bron, Cape Town, 7530, South Africa. Tel no.: 0800 22 3311. Please refer to the detailed professional information (PI) for full prescribing information.

